Journal article
The frequency and clinical associations of opioid use in systemic sclerosis
JL Fairley, D Hansen, S Proudman, J Sahhar, GS Ngian, D Apostolopoulos, J Walker, LV Host, W Stevens, N Ferdowsi, M Tabesh, M Nikpour, L Ross
Rheumatology Advances in Practice | Published : 2024
DOI: 10.1093/rap/rkae144
Abstract
Objective: To define the frequency and associations of opioid use in SSc. Methods: Australian Scleroderma Cohort Study participants meeting ACR/EULAR criteria for SSc were included. Current or previous opioid use was recorded at each visit, with long-term use defined as use on two or more consecutive visits. Groups were compared using two-sample t-test, Wilcoxon rank sum test or chi-squared test. Generalised estimating equations were used to model longitudinal data. Results: Of 1951 participants with a mean age of 46.7 years (S.D. 14.4), 88% were female and 12% had ever received any opioids since SSc onset. Of these, 46% recorded opioid use across multiple consecutive study visits. Digital u..
View full abstractGrants
Awarded by St Vincent's Hospital Melbourne IT Department and Research Endowment Fund (REF)
Awarded by University of Melbourne John Hayden Research Fellowship
Funding Acknowledgements
The ASCS is supported by Janssen, Boehringer Ingelheim, Scleroderma Australia, Scleroderma Victoria, Arthritis Australia, Musculoskeletal Australia (muscle, bone and joint health), Australian Rheumatology Association and St Vincent's Hospital Melbourne IT Department and Research Endowment Fund (REF). J.L.F. holds an NHMRC Postgraduate Scholarship (GNT2013842), an Australian Government Research Training Program Scholarship and the University of Melbourne John Hayden Research Fellowship. M.N. holds an NHMRC Investigator Grant (GNT1176538). L.R. is the recipient of an RACP Australian Rheumatology Association and D.E.V. Starr Research Establishment Fellowship and Melbourne Medical School Strategic Grant for Outstanding Women.